Translational Pathology Core Laboratory
Director: Samuel French, M.D., Ph.D.
Co-Director: Dawn Ward, M.D.
Manager: Clara E. Magyar, Ph.D.
Mailing Address
14-127 Center for Health Sciences
University of California, Los Angeles
Los Angeles, CA 90095-1732
Telephone: (310) 825-1717
Fax: (310) 267-2104
Email: tpcl@mednet.ucla.edu
Website: http://pathology.ucla.edu/tpcl
Major Services
- Human tissue procurement
- Fresh remnant tissues from surgical resections
- Clinical trial biospecimen procurement and processing (biopsies, biofluids)
- Access to archived paraffin blocks
- CAP accredited human tissue biorepository of frozen/paraffin embedded cancer specimens
- Histology services
- Processing, embedding, cutting paraffin/cryostat sections, special stains
- Both human and animal tissues
- Laser capture microdissection (sample preparation and training)
- Immunohistochemistry/immunofluorescence
- Established antibodies and optimization of new antibodies
- Multiplexed immunofluorescence staining (up to 9 biomarkers)
- Digital pathology/image analysis
- Brightfield/fluorescence whole slide scanning
- Automated analysis of brightfield/fluorescence images (from any file type)
- Pathology Consultation Services
- Study design, tissue selection, IRB advice, identification of cases within UCLA archives, slide interpretation
Operating Policies
The investigator submits a "Request for Services" form (available by email request); p39 for recharge and (depending on request) IRB approval is also required.
Drs. Dry and French are available to meet with each investigator to assist in "fine-tuning" critical details of the research requirements, optimal tissue sources (e.g., surgery, autopsy), and the method of preparation. Contact Dr. Magyar (cmagyar@mednet.ucla.edu) to arrange consultations for digital image analysis.
Recharge Rates
Service | JCCC Rate |
---|---|
Tissue procurement (per tissue) | (Price varies according to complexity and processing) $25-$42 |
Histology H&E stain (per slide) | $2 |
IHC/ISH (per slide/section/antibody) | $25 |
TMA preparation |
Please inquire |
Digital slide scan (per slide 20x/40x), brightfield |
$7/$10 |
Digital slide scan (per slide 20x/40x), immunofluorescence | (Price varies according to number of biomarkers and magnification)
$10-$20 |
Image analysis | $25/hour |
Pathology consultation | $187/hour |