- UCLA scientists create a renewable source of cancer-fighting T cells
A study by UCLA researchers is the first to demonstrate a technique for coaxing pluripotent stem cells — which can give rise to every cell type in the body and which can be grown indefinitely in the lab — into becoming mature T cells capable of killing tumor cells.
January 17, 2019 3:00 PMdetail
- UCLA researcher uses big data to help optimize cancer treatment
In this Q&A, Paul Boutros explains how scientists take data, such as DNA sequencing, to design personal treatments
January 16, 2019 8:00 AMdetail
- Researchers discover common markers of tumor hypoxia across 19 cancer types
Researchers have discovered molecular hallmarks of hypoxia in the first-ever pan-cancer analysis of low oxygen in human tumors, with a special focus on prostate cancer.
January 14, 2019 8:00 AMdetail
- UCLA study overturns dogma of cancer metabolism theory – tumors not as addicted to glucose as previously thought
UCLA scientists have discovered that squamous cell skin cancers do not require increased glucose to power their development and growth, contrary to a long-held belief about cancer metabolism.
January 09, 2019 11:00 AMdetail
- Dr. Josh Sasine studies CAR T and other immune system approaches to treat cancer
In this video profile, UCLA’s Dr. Josh Sasine describes his connection to multiple myeloma and why he is looking for new ways to treat this cancer that accumulates in the bone marrow.
January 08, 2019 12:00 PMdetail
- Neurosurgeon-scientist honored for work in the laboratory and the clinic
Dr. Linda Liau, chair of the neurosurgery department at the David Geffen School of Medicine at UCLA, has been awarded the Abhijit Guha Award for her pioneering work on treating brain tumors.
December 21, 2018 8:30 AMdetail
- Three professors elected to the American Society for Clinical Investigation
Dr. Siavash Kurdistani has been elected as members of the American Society for Clinical Investigation, one of the oldest and most esteemed nonprofit honor societies of physician-scientists.
December 20, 2018 9:00 AMdetail
- Study identifies location of DNA that gives clues to hidden cancer mutations
A new study by UCLA scientists shows that enhancers, snippets of DNA that contribute to gene regulation, fall into the same “insulated neighborhoods” or chromatin loops as the target gene and other gene-specific regulatory elements.
December 10, 2018 11:00 AMdetail
- Sprayable gel developed by UCLA-led team could help the body fight off cancer after surgery
A UCLA-led research team has developed a spray gel embedded with immune-boosting drugs that could help fight recurrent cancer.
December 10, 2018 9:00 AMdetail
- Newly identified T cells could play a role in cancer and other diseases
Researchers from the UCLA Jonsson Comprehensive Cancer Center and the La Jolla Institute of Immunology have identified a new type of T cell called a phospholipid-reactive T cell that is able to recognize phospholipids, the molecules that help form cells’ outer membranes.
December 05, 2018 10:00 AMdetail
- UCLA research suggests widely used breast cancer therapy doesn’t cause cognitive decline
UCLA researchers have found that commonly used hormone therapies for women diagnosed with breast cancer do not appear to cause significant cognitive dysfunction following the treatment.
November 28, 2018 11:00 AMdetail
- Cancer researcher named American Association for the Advancement of Science Fellow
Carla Koehler, a professor with the Department of Chemistry and Biochemistry, has been named a Fellow of the American Association for the Advancement of Science. Koehler’s election is an honor bestowed on her by her peers within the Association.
November 27, 2018 10:00 AMdetail
- New FDA-approved therapy targets a variety of cancers
The newly FDA-approved larotrectinib is a targeted cancer therapy. UCLA treated “Little Linda” as part of a trial. She had infantile fibrosacoma. Within days of beginning her treatment, the tumor started shrinking.
November 26, 2018 2:00 PMdetail
- New evidence shows chemotherapy, radiation cancer treatments may be linked to decline in cognitive performance
UCLA researchers conducted a study of breast cancer survivors to better understand if lower activity of telomerase (an enzyme that helps maintain the health of cells) along with DNA damage (a factor in cellular aging) were associated with worse cognitive performance, such as attention and motor skills.
November 26, 2018 10:00 AMdetail
- Young Investigator Awards honor given to UCLA prostate cancer researcher
Dr. Hans David Ulmert, a new member of the UCLA Jonsson Comprehensive Cancer Center, is being honored by the Society for Basic Urologic Research with their annual Young Investigator Awards.
November 15, 2018 9:00 AMdetail
- Researchers identify a mechanism that fuels cancer cells’ growth
UCLA scientists have identified sodium glucose transporter 2, or SGLT2, as a mechanism that lung cancer cells can utilize to obtain glucose, which is key to their survival and promotes tumor growth.
November 14, 2018 11:00 AMdetail
- NIH grant awarded to UCLA researchers to establish Center for the Early Detection of Liver Cancer
A group of researchers from the UCLA Jonsson Comprehensive Cancer Center received a $3.5 million, five-year grant from the National Institute of Health to create a center dedicated to developing an effective and affordable blood-based cancer-screening test to help detect liver cancer early.
November 07, 2018 9:00 AMdetail
- Low-fat diet increases cancer survival rate in mice, study finds
Something as simple as a change in diet can potentially help to increase the cancer survival rate of obese children with acute lymphoblastic leukemia, the most common childhood cancer, according to a new study by UCLA scientists.
October 31, 2018 6:00 PMdetail
- UCLA cancer treatment gave this woman more than just hope
Denise Delatorre felt a lump in her stomach that she knew was serious. She was diagnosed with non-Hodgkin’s lymphoma, one of the most common blood cancers. When chemotherapy didn’t work, she enrolled in UCLA’s first CAR T clinical trial. Today, Denise is in sustained remission. This is her story.
October 31, 2018 11:00 AMdetail
- Two-cells-in-one combo could be platform to bolster leukemia treatment
UCLA researchers have discovered a new protein factor that contributes to a fibroblast cell’s ability to migrate to a wound and participate in its healing process. The study’s results could help scientists prevent cancer cells from using the same mechanisms to move throughout the body and spread.
October 29, 2018 11:00 AMdetail