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JCCC Research Seminar featuring David Shackelford

Mapping metabolic and mitochondrial heterogeneity in lung cancer

Presented by
David Shackelford, Ph.D.
Associate Professor
Department of Pulmonary and Critical Care Medicine

Dr. David Shackelford conducts basic translational cancer research and is focused on uncovering the molecular mechanisms driving carcinogenesis, developing new in vitro and in vivo cancer models, and identifying new personalized therapies to treat cancer based on the tumor’s genetic and molecular alterations. His primary expertise is in signal transduction where he utilizes genetically engineered mouse models of lung cancer to study essential growth and survival pathways in non-small cell lung cancer (NSCLC). By integrating molecular biology, immunohistochemistry and micro PET-CT imaging into preclinical studies he has developed a multifaceted, rapid methodology to analyze tumor development and therapeutic response and to identify new therapeutics with the aim of translating bench discoveries into clinical studies.

Light lunch served

Sponsored by the UCLA Jonsson Comprehensive Cancer Center Signal Transduction and Therapeutics esearch program

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